1Department of Anesthesia and Resuscitation, University Clinics of Kinshasa, DRC
2Department of Anesthesia and Resuscitation, Clinique Caron, France
3Department of Statistics, School of Public Health, University Clinics of Kinshasa, DRC
*Corresponding Author:Jose Mavinga Nyombo
Department of Anesthesia and Resuscitation
University Clinics of Kinshasa
Democratic Republic of the Congo
Tel: +243 815992878; +243898075771
Objective: To set up a program of VAP prevention (ventilator-bundle) then to evaluate its impact on morbidity and mortality of the patients under mechanical ventilation in our service. Patient and Methods: Prospective, mono-centric, quasi-experimental study, before-after type; performed in the intensive care unit of University Clinics of Kinshasa in the Democratic Republic of Congo. The study was conducted in two phases, from February 1st, 2014 to February 15th, 2016. All consecutive patients intubated and mechanically ventilated for more than 48 hours were included. Five preventive measures were implemented. In patients suspected of having VAP (CPIS>6), the diagnosis was made when isolating a pathogen at ≥ 104 CFU/mL in the tracheobronchial aspiration culture. The main outcome measures were the incidence of VAP and the mortality rate. Results: We included 44 patients in phase 1 and 58 patients in phase 2. The basic characteristics of patients were similar in both groups. Compliance with all the measures put in place was improved between the two phases from 0 to 32.75%. The incidence density decreased from 33.74 to 18.05 VAP for 1000 day ventilator, but the mortality was similar in both groups (88.6% vs. 86.0%). Conclusion: The implementation of a « ventilator bundle » has significantly reduced the impact of VAP in our service. However, our study failed to show a decline in mortality.
Ventilator acquired pneumonia, Ventilator-bundle, Intensive care unit.
Research Article – Journal of Infectious Diseases and Medical Microbiology (2018) Volume 2, Issue 3