Curriculum vitaeProfileResearchCollaborationsPublications

PERSONAL INFORMATION

French  Oral, written excellent (Mother tongue)
 English  Oral and written very good
 Lingala  Oral fluent, written good

CONTACT 

E-mail : akatshimarie@yahoo.fr

EDUCATION AND TRAINING

INSTITUTION AND LOCATION

Oxford University, NDM department

DEGREE

DPhil

YEAR CONFERRED

2016

FIELD OF STUDY

Clinical Medicine

Kinshasa School of Public Health, University of Kinshasa Spécialiste en Santé Publique 2004 – 2005 Public Health (Methods in PH, planning and management of Health services, family and community health)
University of Kinshasa, School of Medicine MD 1993 – 2003 General Medicine

POSITION AND EMPLOYMENT

Work date Position and Title Name of organization Job responsibilities
May 2016 to date Associate Professor Kinshasa SPH(University of Kinshasa) Teaching (graduate and undergraduate) and research
June 2016 to date Local PI PAC study KIMORU/ Responsible of clinical and
2015 to date

2010- May 2016

Clinical Director

Senior lecturer

MRC/Oxford

KIMORU Research Unit

Kinshasa SPH

scientific activities and team management

Responsible of clinical and scientific activities and team management

Mother and child health improvement by infectious diseases control (Community health department)

2005 – 2010

Nov 15 -now

2014 -2015

2013-2014

Jan to May 2013

Teaching Assistant

Principal Investigator

on TRAC II study

Principal Investigator

on DHART study

Principal Investigator

on ALN5P study

Investigator on TRAC I study

Kinshasa SPH

Oxford University

Oxford

University

Oxford University

Oxford University

Mother and child health improvement by infectious diseases control (especially malaria)

Technical and scientific management of the trial

Technical and scientific management of the study

Technical and scientific management of the study

Technical and scientific management of the study

2011- 2013

2006 to January1,2010

Investigator of trial on Monitoring antimalarial Treatment efficacy in DRC

Project Director of Pharmacokinetic and pharmacodynamic study of Artesunate in pregnant women in Kinshasa , DRC

Oxford University

University of North Carolina – Kinshasa SPH

Technical and scientific management of the study.

Technical documents development (protocol, forms, SOPs, etc ), study implementation, technical, administrative and financial monitoring, staff recruitment and training, clinical sample overseeing, data management, sponsors interface, manuscript writing.

Oct 09- Jul 10 DRC Co Investigator of the Africa Quinine versus Artesunate in Severe Malaria Trial ( AQUAMAT) Oxford University –Kinshasa School of Public Health Technical documents development (on site SOPs, etc ), study implementation, technical, administrative and financial monitoring, staff recruitment and training, clinical sample overseeing, sponsors interface.
2003- 2004 Project coordinator of study on Tobacco use status during pregnancy in Kinshasa, DRC University of North Carolina – Kinshasa SPH Overseeing the day-to-day clinical, operational and administrative activities of the study, staff training.
2003 Coordinator AZM study: Safe pregnancy by infectious disease control in Kinshasa , DRC University of North Carolina – Kinshasa SPH On site activities operationalisation , data collection and staff management

KEY SKILLS

Clinical and laboratory Research especially clinical trials (Phase I and Phase III), epidemiology of infectious and parasitic diseases. Designing/Implementation of Infectious Diseases Control projects. Project management.

PROFESSIONAL SOCIETIES
2003 Ordre National des Médecins de la République Démocratique du Congo : CNOM 5816
2004

2011

2016

2016

Association des femmes médecins du Congo

Oxford University Student Union

Oxford University Alumni

Association des femmes Professeurs du Congo

POSTERS/ORAL PRESENTATIONS

1. M Onyamboko, D Nanlele, N Goco, A Tshefu, M. Bloch, L Wright, R. Ryder. Pregnant Women’s Knowledge, Attitudes and Behaviors Toward Tobacco in the Democratic Republic of the Congo, 13th World Conference on Tobacco OR Health, July 2006, Washington


2. Onyamboko, MA; Atibu, J, Lokomba V; Meshnick, SR; Douoguih M; Hemingway-Foday J; Koch M; Capparelli E; Fleckenstein, L; Ryder WR; Bose C; Wright L; Tshefu, AK. Pharmacokinetics (PK) and pharmacodynamics (PD) of artesunate (AS) and dihydroartemisinin (DHA) following a single oral dose of artesunate during the 2nd and 3rd trimester of pregnancy .5th MIM PAN – AFRICAN MALARIA CONFERENCE November 2-6,2009 Nairobi, Kenya.


3. Onyamboko , MA; J, Lokomba V; Meshnick, SR; Douoguih M; Hemingway-Foday J; Koch M; Capparelli E; Fleckenstein, L; Ryder WR; Bose C; Wright L; Tshefu, AK. Pharmacokinetics (PK) and pharmacodynamics (PD) of artesunate (AS) and dihydroartemisinin (DHA) following a single oral dose of artesunate during the 2nd and 3rd trimester of pregnancy. 58th American Society of Tropical Medicine and Hygiene Annual conference November 18-22 , 2009, Washington, USA


4. Onyamboko AM , Fanello CI, Wongsaen K, Tarning J, Cheah PY, Dondorp A, Nosten F, White JN, Tshefu KA, NPJ Day. A randomised study to assess the efficacy and tolerability of three artemisinin based combination therapies for the treatment of P. falciparum malaria in the Democratic Republic of Congo.62ND Annual meeting ASTMH,November 13-17, 2013.


5. Marie A. Onyamboko, Caterina I. Fanello, Gareth Turner, Nikki Jackson, Joel Tarning, Francois Nosten, Nick J. White, Antoinette K. Tshefu, Nick P. Day.Comparison of two regimens of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in pregnant women in the Democratic Republic of the Congo. 64th Annual meeting ASTMH,November 13-17, 2015, Philadelphia, USA. Oral presentation and Co-chair of the session.

CONFERENCES AND SEMINAIRES

1. Training on ‘ Diagnostic microscopique du paludisme, tuberculose, VIH /SIDA et Sécurité transfusionnelle. CDC/ATLANTA ; PNLS ;ESP ;PNTS ;PNLT, Kinshasa , DRC, 2003
2. Training on Research methodology, RTI International and NCIHD , Washington DC , June 2004
3. Steering Committee of Global Network for Women’s and Children ‘s Health Research , Washington DC, June 2004
4. Training on Kangaroo Mother Care at Chris Hani Baragwanath Hospital (Affiliated to the University of the Witwatersrand) , Johannesburg, South Africa, Oct 2004
5. Program Management, Monitoring and Evaluation Research , Summer Institute, Application to HIV-AIDS Programs , Nairobi, Kenya, July-August 2005
6. Training in Good Clinical Practice/Good Clinical Laboratory Practice, NIAID, FHI, 2006, Brazzaville/ Kinshasa.
7. Steering Committee of Global Network for Women’s and Children‘s Health Research, Washington DC, February 2008.
8. Project Management Training with Swiss Tropical Institute, Kinshasa , November 2008
9. The 5th PAN AFRICAN MIM Conference , Nairobi , Kenya, November 2-6, 2009
10. The 58th American Society of Tropical Medicine and Hygiene Annual conference November 18-22 , 2009, Washington, USA
11. The TRAC I Investigators meeting, Nairobi, 2010
12. The 64th American Society of Tropical Medicine and Hygiene Annual meeting (ASTMH), November 13-17, 2015, Philadelphia, USA.
13. The TRAC II Investigators meeting, Bangkok, 2016
14. Congres de Parasitologie (CIPIP) du 08 au 10 Decembre 2016, Kinshasa , RDC
15. The 66th American Society of Tropical Medicine and Hygiene Annual meeting (ASTMH), November 5-9, 2017, Baltimore, USA.
16. The 7th PAN AFRICAN MIM Conference , Dakar , Senegal, April 15-20, 2018

  1. Name: Professor Marie A. ONYAMBOKO, MD, MPH,PhD. (onyamboko@unikin.ac.cd et akatshimarie@yahoo.fr).
  1. Titles: Associate Professor, University of Kinshasa, School of Medicine, Kinshasa School of Public Health, Community Health Department. Clinical Director of the Kinshasa Mahidol Oxford Tropical Medicine Research Unit. Principal Investigator of KSPH/Oxford research studies.
  1. Function : KSPH Board Committee member in charge of academic affairs
  2. Field of studies:
  • Epidemiology of infectious disease especially malaria. Control of malaria in pregnant women and children. Antimalaral drugs pharmacokinetics and pharmacodynamics. Antimalarial drug resistance.
  • Improvement of maternal and child health in low income settings (Kangaroo Mother Care; Tobacco impact in mothers an children health)
  1. Field of interest: Infectious diseases control and Maternal and Child Health

Prof Marie Onyamboko ‘s diverse interests are  the epidemiology, pathophysiology and treatment of malaria particularly in pregnant women and children . This interest extend to  Ebola, Yellow fever, Dengue, Zika  and other communicable diseases affecting poor population in the DRC, Africa and beyond. Her particular interests at present include the prevention of antimalarial drug resistance using artemisinin-based combinations and treatment of severe malaria.

  1. Skills and expertise: Tropical diseases, Drug resistance, Tropical Medicine, Malaria, Clinical Trials
  2. Location: Kinshasa, DRC
  3. Research Group: Kinshasa Mahidol Oxford Tropical Medicine Research Unit (KIMORU)
  4. Studies:
  • Medical studies (MD title): School of Medcine, University of Kinshasa
  • Master in Public Health : Kinshasa School of Public Health
  • DPhill: University of Oxford, Nuffield Department of Clinical Medicine,

Kellog College

Assessing the safety of low dose primaquine in Plasmodium falciparum infected African children with glucose 6 phosphate dehydrogenase deficiency (PAC Study)

The aim of this study is to provide evidence for drug policy on the safety of the WHO recommended single low dose primaquine regimen when used under close to routine conditions to G6PD deficient  African children with acute uncomplicated P. falciparum. This study proposal answers the WHO’s call for more research on SLDPQ and will fill a number of substantial knowledge gaps in young African children, including the tolerability of SLDPQ at the WHO recommended dose in children with high biomass falciparum infections and often concomitant anaemia, the factors associated with the development of severe/profound anaemia, the Pharmacokinetic of Primaquine and the  prevalence rates of CYP 2D6 polymorphisms and their relationships to PQ PK.

Sponsor : University of Oxord/MRC   Role KSPH : DRC Site Principal Investigator

Baseline assessment of neonatal hyperbilirubinaemia in a cohort of new-borns in Kinshasa, Democratic Republic of Congo (NNJ Study)

The primary objective is to evaluate the prevalence of neonatal hyperbilirubinaemia in a cohort of 306 in-hospital consecutive live births. The results of this survey will provide essential baseline data for the community. If the frequency of the NH and severe NH in the area is higher than routinely reported, prompt and appropriate management guidelines can be put in place to decrease neonatal mortality and neurological disabilities. At the same time, the use of better diagnostic tools for identification of NH and associated risk factors can be implemented. Likewise, a program of community engagement to teach mothers how to recognize signs of hyperbilirubinaemia can be piloted as lack of education and awareness of this condition is a well-known additional risk factor.

Sponsor : University of Oxord/MRC   Role KSPH : Principal Investigator

Evaluating the renoprotective effect of acetaminophen in pediatric severe falciparum malaria: A randomized controlled trial

The overall goal is to assess the renoprotective effect of APAP in severe malaria. Our hypothesis is that APAP will reduce kidney dysfunction by inhibiting CFH-mediated oxidative damage. The study will also assess APAP’s: (i) safety, (ii) effects on fever, coma and parasite clearance, and (iii) pharmacokinetics and pharmacodynamics.

Sponsor : Canadian Research Council   Role KSPH : Principal Investigator

Development project for Triple Artemisinin Combination Therapies (DeTACT)

The goal of the project is to provide the evidence and the products to support a global change in antimalarial treatment. The impact expected is progress to malaria elimination and, critically, prevention of a potentially catastrophic reversal of all recent gains in malaria control because of the spread of ACT resistance.

Two quality assured triple artemisinin combination therapies (TACTs) which have been extensively tested for efficacy, safety and tolerability in both children (mainly Africa) and adults (mainly Asia) will be delivered by the end of this project. To facilitate policy transition the project will assess the market positioning of TACTs as a new first-line treatment for falciparum malaria in both African and Asian malaria endemic countries, and model the potential health and economic impact of delaying the emergence and spread of multi-drug resistant falciparum malaria by switching first-line treatments to TACTs. This project should provide new effective and safe treatments for falciparum malaria not only in countries currently threatened by untreatable malaria (SE Asia), but also in endemic countries threatened by the importation of these drug resistant strains (South Asia and Africa).

  • University of Oxford, Nuffield Clinical Medicine Department
  • Mahidol Oxford Tropical Medicine Research Unit
  • Swiss Tropical Institute
  • Canadian Research Council

PUBLIC ENGAGEMENT

KIMORU has set since 2014 ie five years now a service to the community. It is the passive screening and treatment of uncomplicated malaria in suburban areas of Kinshasa.

This activity is totally free and is continuous ie 7 day a week, 24hours a days since its beginning.

We are supported in this activity with SANRU/Global Fund.

By December 2018, we have screened 35,211 symptomatic children attending KIMORU and treated 23,553 for uncomplicated malaria with an ACT (Rapid Diagnostic Test positive).

W. Robert Taylor, Htee Khu Naw, Kathryn Maitland, Thomas N. Williams, Melissa Kapulu,

Umberto D’Alessandro, James A. Berkley, Philip Bejon, Joseph Okebe, Jane Achan,

Alfred Ngwa Amambua, Muna Affara6, Davis Nwakanma6, Jean-Pierre van Geertruyden, Muhindo Mavoko,Pascal Lutumba, Junior Matangila, Philipe Brasseur, Patrice Piola, Rindra Randremanana, Estrella Lasry,Caterina Fanello, Marie Onyamboko, Birgit Schramm, Zolia Yah, Joel Jonesˆ, Rick M. Fairhurst,Mahamadou Diakite, Grace Malenga, Malcolm Molyneux, Claude Rwagacondo, Charles Obonyo,Endalamaw Gadisa, Abraham Aseffa, Mores Loolpapit, Marie-Claire Henry, Grant Dorsey, Chandy John,Sodiomon B. Sirima, Karen I. Barnes, Peter Kremsner, Nicholas P. Day, Nicholas J. White and Mavuto Mukaka.  Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria –a proposed model-derived age-based regimen for sub-Saharan Africa. BMC Medicine (2018) 16:11

DOI 10.1186/s12916-017-0990-6


Marie Onyamboko et al. The pharmacokinetic, efficacy and safety of a longer course of artemether-lumefantrine for the treatment of uncomplicated malaria in pregnancy in the Democratic Republic of the Congo. 2018. Under review.


Fanello C, Onyamboko M, Lee SJ, Woodrow C, Setaphan S, Chotivanich K, Buffet P, Jaureguiberry S, Rockett K, Stepniewska K, Day NPJ, White NJ , Dondorp AM. (2017). “Post-treatment haemolysis in African children with hyperparasitaemic falciparum malaria; a randomized comparison of artesunate and quinine” BMC Infect Dis. 2017 Aug 17;17(1):575.


Roberto Amato, Olivo Miotto, Charles Woodrow, Jacob Almagro-Garcia, Ipsita Sinha, Susana Campino, Daniel Mead, Eleanor Drury, Mihir Kekre, Mandy Sanders, Alfred Amambua-Ngwa, Chanaki Amaratunga, Lucas Amenga-Etego, Tim JC Anderson, Voahangy Andrianaranjaka, Tobias Apinjoh, Elizabeth Ashley, Sarah Auburn, Gordon A Awandare, Vito Baraka, Alyssa Barry, Maciej F Boni, Steffen Borrmann, Teun Bousema, Oralee Branch, Peter C Bull, Kesinee Chotivanich, David J Conway, Alister Craig, Nicholas P Day, Abdoulaye Djimdé, Christiane Dolecek, Arjen M Dondorp, Chris Drakeley, Patrick Duffy, Diego F Echeverri-Garcia, Thomas G Egwang, Rick M Fairhurst, Md. Abul Faiz, Caterina I Fanello, Tran Tinh Hien, Abraham Hodgson, Mallika Imwong, Deus Ishengoma, Pharath Lim, Chanthap Lon, Jutta Marfurt, Kevin Marsh, Mayfong Mayxay, Victor Mobegi, Olugbenga Mokuolu, Jacqui Montgomery, Ivo Mueller, Myat Phone Kyaw, Paul N Newton, Francois Nosten, Rintis Noviyanti, Alexis Nzila, Harold Ocholla, Abraham Oduro, Marie Onyamboko, Jean-Bosco Ouedraogo, Aung Pyae Phyo, Christopher V Plowe, Ric N Price, Sasithon Pukrittayakamee, Milijaona Randrianarivelojosia, Pascal Ringwald, Lastenia Ruiz, David Saunders, Alex Shayo, Peter Siba, Shannon Takala-Harrison, Thuy-Nhien Nguyen Thanh, Vandana Thathy, Federica Verra, Nicholas J White, Ye Htut, Victoria J Cornelius, Rachel Giacomantonio, Dawn Muddyman, Christa Henrichs, Cinzia Malangone, Dushyanth Jyothi, Richard D Pearson, Julian C Rayner, Gilean McVean, Kirk Rockett, Alistair Miles, Paul Vauterin, Ben Jeffery, Magnus Manske, Jim Stalker, Bronwyn MacInnis, Dominic P Kwiatkowski, for the MalariaGEN Plasmodium falciparum Community.Genomic epidemiology of the current wave of artemisinin resistant malaria. BioRxiv preprint first posted online May. 22, 2015; doi: http://dx.doi.org/10.1101/019737.


Roberto Amato (and 96 authors including Marie Onyamboko). Genomic epidemiology of artemisinin resistant malaria MalariaGEN Plasmodium falciparum Community Project. eLife Sciences March 2016; DOI: 10.7554/eLife.08714.


WWARN Parasite Clearance Study Group. Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis. Malaria Journal (2015) 14:359.DOI 10.1186/s12936-015-0874-1


Freek de Haan, Marie A Onyamboko, Caterina I Fanello, Charles J Woodrow, Yoel Lubell, Wouter P C Boon, Arjen M Dondorp. Exploring health practitioners’ acceptability of a prospective semi-quantitative pfHRP2 device to define severe malaria in the Democratic Republic of Congo. Malaria Journal 2015 15;14(1):503. Epub 2015 Dec 15.


Salim Abdulla, Elizabeth A Ashley, Quique Bassat, Delia Bethell, Anders Björkman, Steffen Borrmann, Umberto D’Alessandro, Prabin Dahal, Nicholas P Day, Mahamadou Diakite, Abdoulaye A Djimde, Arjen M Dondorp, Socheat Duong, Michael D Edstein, Rick M Fairhurst, M Abul Faiz, Catherine Falade, Jennifer A Flegg, Carole Fogg, Raquel Gonzalez, Brian Greenwood, Philippe J Guérin, Jean-Paul Guthmann, Kamal Hamed, Tran Tinh Hien, Ye Htut, Elizabeth Juma, Pharath Lim, Andreas Mårtensson, Mayfong Mayxay, Olugbenga A Mokuolu, Clarissa Moreira, Paul Newton, Harald Noedl, Francois Nosten, Bernhards R Ogutu, Marie A Onyamboko, Seth Owusu-Agyei, Aung Pyae Phyo, Zul Premji, Ric N Price, Sasithon Pukrittayakamee, Michael Ramharter, Issaka Sagara, Youry Se, Seila Suon, Kasia Stepniewska, Stephen A Ward, Nicholas J White, Peter A Winstanley.Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis. Malar J 2015 Sep 22; 14:359. Epub 2015 Dec 22.


Olivo Miotto, Roberto Amato, Elizabeth A Ashley, Bronwyn MacInnis, Jacob Almagro-Garcia, Chanaki Amaratunga, Pharath Lim, Daniel Mead, Samuel O Oyola, Mehul Dhorda, Mallika Imwong, Charles Woodrow, Magnus Manske, Jim Stalker, Eleanor Drury, Susana Campino, Lucas Amenga-Etego, Thuy-Nhien Nguyen Thanh, Hien Tinh Tran, Pascal Ringwald, Delia Bethell, Francois Nosten, Aung Pyae Phyo, Sasithon Pukrittayakamee, Kesinee Chotivanich, Char Meng Chuor, Chea Nguon, Seila Suon, Sokunthea Sreng, Paul N Newton, Mayfong Mayxay, Maniphone Khanthavong, Bouasy Hongvanthong, Ye Htut, Kay Thwe Han, Myat Phone Kyaw, Md Abul Faiz, Caterina I Fanello, Marie Onyamboko, Olugbenga A Mokuolu, Christopher G Jacob, Shannon Takala-Harrison, Christopher V Plowe, Nicholas P Day, Arjen M Dondorp, Chris C A Spencer, Gilean McVean, Rick M Fairhurst, Nicholas J White, Dominic P Kwiatkowski. Genetic architecture of artemisinin-resistant Plasmodium falciparum. Nat Genet 2015 Mar 19;47(3):226-34. Epub 2015 Jan 19.


Sachel Mok, Elizabeth A Ashley, Pedro E Ferreira, Lei Zhu, Zhaoting Lin, Tomas Yeo, Kesinee Chotivanich, Mallika Imwong, Sasithon Pukrittayakamee, Mehul Dhorda, Chea Nguon, Pharath Lim, Chanaki Amaratunga, Seila Suon, Tran Tinh Hien, Ye Htut, M Abul Faiz, Marie A Onyamboko, Mayfong Mayxay, Paul N Newton, Rupam Tripura, Charles J Woodrow, Olivo Miotto, Dominic P Kwiatkowski, François Nosten, Nicholas P J Day, Peter R Preiser, Nicholas J White, Arjen M Dondorp, Rick M Fairhurst, Zbynek Bozdech. Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance. Science 2015 Jan 11;347(6220):431-5. Epub 2014 Dec 11.


E.A. Ashley, M. Dhorda, R.M. Fairhurst, C. Amaratunga, P. Lim, S. Suon, S. Sreng, J.M. Anderson, S. Mao, B. Sam, C. Sopha, C.M. Chuor, C. Nguon, S. Sovannaroth, S. Pukrittayakamee, P. Jittamala, K. Chotivanich, K. Chutasmit, C. Suchatsoonthorn, R. Runcharoen, T.T. Hien, N.T. Thuy-Nhien, N.V. Thanh, N.H. Phu, Y. Htut, K-T. Han, K.H. Aye, O.A. Mokuolu, R.R. Olaosebikan, O.O. Folaranmi, M. Mayxay, M. Khanthavong, B. Hongvanthong, P.N. Newton, M.A. Onyamboko, C.I. Fanello, A.Tshefu, N. Mishra, N. Valecha, A.P. Phyo, F. Nosten, P. Yi, R. Tripura,S. Borrmann, M. Bashraheil, J. Peshu, M.A. Faiz, A. Ghose, M.A. Hossain, R. Samad, M.R. Rahman, M.M. Hasan, A. Islam, O. Miotto, R. Amato, B. MacInnis, J. Stalker, D.P. Kwiatkowski, Z. Bozdech, A. Jeeyapant, P.Y. Cheah, Takulthaew, J. Chalk,B. Intharabut, K. Silamut, S.J. Lee, B. Vihokhern, C. Kunasol, M. Imwong, J. Tarning, W.J. Taylor, S. Yeung, C.J. Woodrow, J.A. Flegg, D. Das, J. Smith, M. Venkatesan, C.V. Plowe, K. Stepniewska, P.J. Guerin, A.M. Dondorp, N.P. Day, and N.J. White, for the Tracking Resistance to Artemisinin Collaboration (TRAC). Spread of Artemisinin Resistance in Plasmodium falciparum Malaria. The new england journal of medicine original, Volume 371, number 5: pages 411-423.


Onyamboko MA, Fanello CI Wongsaen K , Tarning J, Cheah PY, Tshefu AK, Dondorp AM, Nosten F, White NJ, Day NP . A  Randomized Comparison of the Efficacies and Tolerabilities of Three Artemisinin-Baed Combination Treatments for Children with Acute Plasmodium falciparum Malaria in the Democratic Republic of the Congo. Antimicrobial Agents and Chemotherapy , Volume 58, number 9, September 2014


Thiranut Ramutton, Ilse C E Hendriksen, Juliet Mwanga-Amumpaire, George Mtove, Rasaq Olaosebikan, Antoinette K Tshefu, Marie A Onyamboko, Corine Karema, Kathryn Maitland, Ermelinda Gomes, Samwel Gesase, Hugh Reyburn, Kamolrat Silamut, Kesinee Chotivanich, Kamoltip Promnares, Caterina I Fanello, Lorenz von Seidlein, Nicholas P J Day, Nicholas J White, Arjen M Dondorp, Mallika Imwong, Charles J Woodrow. Sequence variation does not confound the measurement of plasma PfHRP2 concentration in African children presenting with severe malaria. Malar J 2012 16;11:276. Epub 2012 Aug 16.


Lorenz von Seidlein,Rasaq Olaosebikan,Ilse C. E. Hendriksen, Sue J. Lee,Olanrewaju Timothy Adedoyin, Tsiri Agbenyega, Samuel Blay Nguah,Kalifa Bojang,Jacqueline L. Deen,Jennifer Evans,Caterina I. Fanello, Ermelinda Gomes,Al_nia Jose´ Pedro,Catherine Kahabuka,Corine Karema,Esther Kivaya,Kathryn Maitland,Olugbenga A. Mokuolu, George Mtove, Juliet Mwanga-Amumpaire,Behzad Nadjm,Margaret Nansumba,Wirichada Pan Ngum,Marie A. Onyamboko,Hugh Reyburn,Tharisara Sakulthaew,Kamolrat Silamut,Antoinette K. Tshefu, Noella Umulisa,Samwel Gesase,Nicholas P. J. Day,Nicholas J. White,andArjen M. Dondorp. Predicting the Clinical Outcome of Severe Falciparum Malaria in African Children: Findings

From a Large Randomized Trial: Clinical Infectious Diseases Advance Access published March 12, 2012.


Morris CA; Onyamboko  MA; J, Lokomba V; Meshnick, SR; Douoguih M; Hemingway-Foday J; Koch M; Capparelli E;Ryder WR; DL Wesche; Bose C; Wright L; Tshefu, AK; Fleckenstein L. Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with malaria : Malaria Journal 2011, May 8;10:114.PMID: 21548983[PubMed – indexed for MEDLINE].


Marie A Onyamboko, Steven R Meshnick, Lawrence Fleckenstein, Matthew A Koch, Joseph Atibu, Victor Lokomba, Macaya Douoguih, Jennifer Hemmingway-Foday, David Wesche, Robert W Ryder, Carl Bose, Linda L Wright, Antoinette K Tshefu and Edmund V Capparelli . Pharmacokinetics and pharmacodynamics of artesunate and dihydroartemisinin following oral treatment in pregnant women with asymptomatic Plasmodium falciparum infections in Kinshasa DRC. Malaria Journal 2011, 10:49doi:10.1186/1475-2875-10-49. Published 28 February 2011.


Arjen M Dondorp, Caterina I Fanello, Ilse CE Hendriksen, Ermelinda Gomes, Amir Seni, Kajal D Chhaganlal, Kalifa Bojang, Rasaq Olaosebikan, Nkechinyere Anunobi, Kathryn Maitland, Esther Kivaya, Tsiri Agbenyega, Samuel Blay Nguah, Jennifer Evans, Samwel Gesase, Catherine Kahabuka, George Mtove, Behzad Nadjm, Jacqueline Deen, Juliet Mwanga-Amumpaire, Margaret Nansumba, Corine Karema, Noella Umulisa, Aline Uwimana, Olugbenga A Mokuolu, Olanrewaju T Adedoyin, Wahab BR Johnson, Antoinette K Tshefu, Marie A Onyamboko, Tharisara Sakulthaew, Wirichada Pan Ngum, Kamolrat Silamut, Kasia Stepniewska, Charles J Woodrow, Delia Bethell, Bridget Wills, Martina Oneko, Tim E Peto, Lorenz von Seidlein, Nicholas PJ Day, Nicholas J White, for the AQUAMAT group . Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial. The Lancet, Volume 376, Issue 9753, Pages 1621 – 1622, 13 November 2010.


Elwyn Chomba, Antoinette Tshefu, Marie Onyamboko, Christine Kaseba-Sata, Janet B. Moore, Elizabeth M. McClure, Nancy Moss, Norman Goco, Michele Bloch, Robert Goldenberg. Tobacco Use and Secondhand smoke Exposure during Pregnancy in two African Countries: Zambia and the Democratic Republic of Congo ; Acta Obstetricia et Gynecologica Scandinavica ID 461078, Feb 2010.


Muhammad Masood Kadir,Elizabeth M. McClure, Shivaprasad S. Goudar,Ana L.Garces,Janet Moore, Marie Onyamboko,Christine Kaseba,Fernando Althabe,Eduardo E. Castilla, Salvio Freire,Sailajanandan Parida,Sarah Saleem,Linda L. Wright,Robert  L. Goldenberg   and the Global Network Tobacco Study Group. Exposure of Pregnant Women to Indoor Air Pollution: A study from 9 Low and and Middle Income Countries . Acta Obstetricia et Gynecologica Scandinavica. November 2009.


Michele Bloch, Fernando Althabe, Marie Onyamboko, Christine Kaseba-Sata, Eduardo E. Castilla, Salvio Freire, Ana L. Garces, Sailajanandan Parida, Shivaprasad S. Goudar,Muhammad Masood Kadir, Norman Goco, Jutta Thornberry, Magdalena Daniels, Janet Bartz,Tyler Hartwell, Nancy Moss,Robert Goldenberg. Tobacco Use and Secondhand Smoke Exposure During Pregnancy: An investigative Survey of Women in 9 Developing Nations10.2105/AJPH.2007.117887